Detector, LCMS Electron Multiplier

In liquid chromatography-mass spectrometry (LC-MS) systems, electron multipliers serve as critical detectors that identify and amplify ions based on their mass-to-charge ratios. These detectors operate through a process called secondary electron emission, where incoming ions strike a surface, causing the release of secondary electrons. These electrons are then multiplied through a series of dynodes, resulting in a measurable signal proportional to the ion quantity. This amplification process enables the detection of even trace amounts of analytes, enhancing the sensitivity and accuracy of LC-MS analyses.